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Abstract #3013

In-vivo detection of diffusive water transport in human eye using high-resolution diffusion weight imaging

Jiancheng Zhuang 1 and Bosco S. Tjan 1

1 University of Southern California, Los Angeles, California, United States

We describe an approach of using a readout-segmented echo-planar imaging sequence combined with parallel imaging and a two-dimensional navigator-based reacquisition to investigate the diffusive water transport in in-vivo human eyes. The results show the difference of water diffusive movement across different eye structures. It demonstrates feasibility of in-vivo detection of water transport in human eyes at a high spatial resolution (0.38 mm by 0.38 mm in-plane resolution) on a typical clinic scanner by using this readout-segmented echo-planar imaging sequence.

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