Abstract #3023
Characterizing the diffusion properties of blood
Carsten Funck 1 , Frederik Bernd Laun 1 , and Andreas Wetscherek 1
1
Medical Physics In Radiology, German Cancer
Research Center (DKFZ), Heidelberg, Germany
Aim of this work was to measure the diffusion
coefficient of human blood samples dependent on
diffusion time T and diffusion gradient profile. A
phantom is presented which allows one to maintain the
sample temperature and to prevent the blood cells from
sedimentation. Measured ADCs decrease with increasing T
for the flow-compensated gradient profile and stabilize
on a lower level in the bipolar case. The effects can be
explained considering blood as a multi-compartment
system. Differences between individual blood samples
are, however, large compared to these variations. IVIM
applications might benefit from individually measured
diffusion coefficients of blood.
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