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Abstract #3051

Prospective Glioma Grading Using Single Dose Dynamic Contrast Enhanced MRI Perfusion

Aprajita Mehta 1 , Krishan K Jain 1 , Prativa Sahoo 2 , Bhaswati Roy 1 , Ritu Tyagi 1 , Ram K S Rathore 3 , Rana Patir 4 , Sandeep Vaishya 4 , Neeraj Prakash 5 , Nandini Vasudev 5 , and Rakesh K Gupta 1

1 Radiology, Fortis Memorial Research Institute, Gurgaon, India, 2 Philips Healthcare, Philips India Ltd, Gurgaon, India, 3 Dept of Mathematics, Indian Institute of Technology, Kanpur, India, 4 Neurosurgery, Fortis Memorial Research Institute, Gurgaon, India, 5 Pathology, Fortis Memorial Research Institute, Gurgaon, India

It is important to differentiate high and low grade gliomas as treatment strategies are different for different grade of gliomas. Prospective grading of gliomas is helpful in explaining the prognosis to patient and where surgery or biopsy of tumor is difficult, clinical decision may be taken on the basis of perfusion imaging. We planned this study to evaluate the relative sensitivity and specificity of Dynamic Contrast Enhanced MR perfusion with single dose contrast in prospective evaluation of glioma grading. Without additional dose of contrast, perfusion study could be added to the routine brain tumor imaging protocol in differentiating the grade of gliomas.

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