Abstract #3281
Quantitative T 2 and T 2 * relaxometry of hippocampal subfields
Md Nasir Uddin 1 , Yushan Huang 2 , Nikolai V Malykhin 1,2 , and Alan H Wilman 1
1
Biomedical Engineering, University of
Alberta, Edmonton, Alberta, Canada,
2
Centre
for Neuroscience, University of Alberta, Edmonton,
Alberta, Canada
Hippocampal subfields are affected selectively in
different disease processes but the interpretations are
mostly limited to accurate volume measurements.
Quantitative T
2
or
T
2
* relaxometry using high field MRI may be a
more sensitive measure for hippocampal subfields
compared to volumetric measurements. Here we investigate
the absolute measures of spin-echo T
2
and
gradient-echo T
2
* of the hippocampal
subfields at 4.7 T using stimulated echo compensation
and susceptibility compensation.
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