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Abstract #3285

Simultaneous Dual-frequency Range Conductivity Mapping MR Method for Tissue Characterization: In Vivo Canine Brain Disease Model Study

Woo Chul Jeong 1 , Min Oh Kim 2 , Saurav ZK Sajib 1 , Ji Eun Kim 1 , Hyung Joong Kim 1 , Oh In Kwon 3 , Dong Hyun Kim 2 , and Eung Je Woo 1

1 Kyung Hee University, Yongin, Gyeonggi, Korea, 2 Yonsei University, Seoul, Korea, 3 Konkuk University, Seoul, Korea

Electrical tissue conductivity is primarily determined by concentration and mobility of ions in intra- and extra-cellular fluids. The conductivity of biological tissues show frequency-dependent behavior and its values at different frequencies may provide useful diagnostic information. MR-based tissue property mapping are widely used imaging techniques which provided unique conductivity contrast at different frequency ranges. Recently, new method for data acquisition and reconstruction for low- and high-frequency conductivity images from a single MR scan was proposed. In this study, we applied the simultaneous dual-frequency range conductivity mapping to enhance its clinical potentials through in vivo disease model animal imaging.

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