Meeting Banner
Abstract #3312

DirEct Complex signAl Fitting (DECAF) for multi-compartment analysis in white matter

Yoonho Nam 1 , Dong-Hyun Kim 2 , and Jongho Lee 1

1 Department of Electrical and Computer Engineering, Seoul National University, Seoul, Seoul, Korea, 2 Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea

Recent studies have demonstrated that signals from three water compartments in white matter have different B0 orientation dependent frequency offsets. This observation improved data fitting results in GRE-based MWI by using complex signal fitting as compared to magnitude signal fitting. However, the complex signal fitting approaches applied in the previous studies required several pre-processing steps including a nonlocal background field removal step. Therefore, the results were strongly influenced by them. In this study, we propose a new fitting method that does not require a prior background field removal step. This method shows improvement in parameter estimation.

This abstract and the presentation materials are available to members only; a login is required.

Join Here