Reduced FOV Amide Proton Transfer on Brain Tumor
Chien-Yuan Eddy Lin 1,2 , Bing Wu 2 , Zhongping Zhang 2 , Zhenyu Zhou 2 , Ai-Chi Chen 3 , and Chi-Ren Chen 3
GE Healthcare, Taipei, Taiwan,
Healthcare China, Beijing, China,
of Radiology, Taipei Medical University - Shuang Ho
Hospital, New Taipei City, Taiwan
Amide proton transfer (APT) is capable of detecting the
contrast to the protein level. High-resolution APT may
be required for assessing subtle change of pathology.
However, it is difficult to acquire APT data with
high-resolution due to long scan time required for
multiple acquisitions at different frequencies. As a
result, a recently developed reduced field-of-view (rFOV)
APT sequence was employed to this study and a small
brain tumor (size < 0.8 cm
) was used to
evaluate the clinical performance of rFOV APT.
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