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Abstract #3341

Reduced FOV Amide Proton Transfer on Brain Tumor

Chien-Yuan Eddy Lin 1,2 , Bing Wu 2 , Zhongping Zhang 2 , Zhenyu Zhou 2 , Ai-Chi Chen 3 , and Chi-Ren Chen 3

1 GE Healthcare, Taipei, Taiwan, 2 GE Healthcare China, Beijing, China, 3 Department of Radiology, Taipei Medical University - Shuang Ho Hospital, New Taipei City, Taiwan

Amide proton transfer (APT) is capable of detecting the contrast to the protein level. High-resolution APT may be required for assessing subtle change of pathology. However, it is difficult to acquire APT data with high-resolution due to long scan time required for multiple acquisitions at different frequencies. As a result, a recently developed reduced field-of-view (rFOV) APT sequence was employed to this study and a small brain tumor (size < 0.8 cm 3 ) was used to evaluate the clinical performance of rFOV APT.

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