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Abstract #3485

Imaging macaque cortical myeloarchitecture

Frank Q Ye 1 and Xiaomin Yue 2

1 Neurophysiology Imaging Facility, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, United States, 2 Laboratory of Brain Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, United States

Imaging cortical myeloarchitechture in-vivo is valuable for study brain anatomy and functional organization. With improved spatial resolution and sensitivity, T1 imaging may allow precise mapping of cortical myelination distribution and reveal subtle abnormalities underlying developmental brain disorders. We report here a high resolution imaging protocol optimized for anesthetized rhesus monkey studies. The sensitivity and resolution provided by our implementation afford us to observe the V2 CO stripes, a known architectonic features that have been visible in histology but have not been observed previously using MRI in a living brain.

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