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Abstract #3502

Fluid-Attenuated Three-Dimensional Structural Brain MRI Using Inversion-Recovery-Prepared DANTE-FLASH (IR-DASH)

Linqing Li 1 , Moises Hernandez 1 , and Peter Jezzard 1

1 Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom

DANTE pulse trains can be used to suppress moving blood signal with minimal impact to the static tissue signal. We introduce an inversion recovery prepared 3D DANTE-FLASH (denoted as IR-DASH) that is able to generate 1 mm isotropic resolution full brain images with attenuated fluids (arterial blood and CSF) signal and comparable CNR(WM/GM) to conventional MP-RAGE images. The preliminary results showed that segmentation of grey matter could be significantly improved due to the blood suppression of DANTE pulse trains compared with conventional MP-RAGE brain structure images.

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