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Abstract #3548

Three shape patterns of subcortical structures in medication-nave first-episode schizophrenia patients revealed by morphometric descriptor and cluster analysis

Huaiqiang Sun 1 , Su Lui 1 , Haoyang Xing 1 , Xiaoqi Huang 1 , and Qiyong Gong 1

1 Huaxi MR Research Center, West China Hospital of Sichuan University, Chengdu, China

Three shape patterns of subcortical structures in medication-nave first-episode schizophrenia patients was identified according to the deformation parameters between patient individuals and the atlas constructed from matched healthy controls. Patients belong to different patterns did not differ in demographic features but in clinical symptoms. The shape pattern revealed in this study may reflect distinct underlying pathology.

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