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Abstract #3569

Corticostriatal Connectivity in Violent Offenders with Schizophrenia

Xinyu Hu 1 , Yi Liao 1 , Lizhou Chen 1 , Lei Li 1 , Ming Zhou 1 , Qi Liu 1 , Junmei Hu 2 , Qiyong Gong 1 , and Xiaoqi Huang 1

1 Huaxi MR Research Center (HMRRC), Department of Radiology,West China Hospital of Sichuan University, Chengdu, Sichuan, China, 2 School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China

The association between schizophrenia and violent behavior has significant clinical and social implications. Although previous studies had proved that alterations in the basal ganglia, predominantly the striatum, constitute important characteristics of neural pathology in schizophrenia, the relationship between functional connectivity of striatum and severely violent behaviors still remains unknown. The aim of the current study is to explore the characteristic functional connectivity in a subgroup of schizophrenia patients with severe violent behavior and its relationship with clinical measurements.

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