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Abstract #3585

Investigation of Global effect of ischemic stroke based on oxygen extraction fraction estimation

Lijuan Zhang 1 , Caiyun Shi 1 , Chunxiang Jiang 1 , Li Yi 2 , Guoxi Xie 1 , Xiaojing Long 1 , and Yang Liu 2

1 SIAT, Chinese Academy of Sciences, Shenzhen, Guangdong, China, 2 Peiking University Shenzhen Hospital, Guangdong, China

Ischemic stroke (IS) leads to local metabolic and functional impairment in the vicinity of the lesion. However, the global effect of IS remains to be clarified.In this study we presented the global effect of IS by estimating the cerebral oxygen extraction fraction (OEF) based on the magnetic resonance susceptibility weighted imaging.This preliminary study may provide a meaningful reference for future researches towards a better understanding of the disease dynamic of IS.

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