Can high-resolution T1W 3-Dimensional (3D) gradient recalled echo (GRE) with 2-Point Dixon derived fat-water separation (FLEX) replace conventional T1W Turbo Spin-Echo (TSE) imaging for assessment of prostate cancer?
Karim B Samji 1,2 , Abdulmohsen Alrashed 1,2 , Wael M Shabana 1,2 , Matthew DF McInnes 1,2 , and Nicola Schieda 1,2
Department of Medical Imaging, The Ottawa
Hospital, Ottawa, ON, Canada,
of Ottawa, Ottawa, ON, Canada
T1W TSE imaging is fundamental for prostate cancer
staging with MRI. This study compared a modified
high-resolution free breathing 2-Point Dixon GRE
sequence with fat-water separation (FLEX-LAVA) to T1W
TSE as a potential time saving measure. There was no
difference in detection of nodal or skeletal metastases
and image quality was comparable or slightly improved
with FLEX-LAVA. Our results suggest that T1W TSE can be
safely replaced in prostate cancer MRI examinations
using a high resolution 2-Point Dixon GRE sequence
therefore decreasing examination time.
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