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Abstract #3654

Chemical shift encoding-based water-fat imaging of skeletal muscle in the presence of fat resonance shift and phase errors

Stefan Ruschke 1 , Holger Eggers 2 , Hendrik Kooijman 3 , Pia M. Jungmann 1 , Axel Haase 4 , Ernst J. Rummeny 1 , Thomas Baum 1 , and Dimitrios C. Karampinos 1

1 Department of Diagnostic and Interventional Radiology, Technische Universitt Mnchen, Munich, Bayern, Germany, 2 Philips Research, Hamburg, Hamburg, Germany, 3 Philips Healthcare, Hamburg, Hamburg, Germany, 4 Zentralinstitut fr Medizintechnik, Technische Universitt Mnchen, Garching, Bayern, Germany

Chemical shift encoding-based water-fat imaging has been emerging for quantifying skeletal muscle fat content. In regions with low fat content, magnitude-based techniques have been used to overcome the sensitivity of complex-based techniques to phase errors. However, magnitude-based techniques can become unstable for certain combinations of echo times, when the chemical shift separation between water and fat is not known, e.g. due to the susceptibility-induced fat resonance shift effects in skeletal muscle. The present study aims to characterize complex-based and magnitude-based methods for water-fat separation in skeletal muscle, where both fat resonance shift and phase errors can be present.

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