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Abstract #3676

Simultaneous MPRAGE and Non-Contrast MRA with Prospective Motion Correction using Volumetric Navigators

John W Grinstead 1 , Himanshu Bhat 2 , M. Dylan Tisdall 3 , Andre van der Kouwe 3 , William Rooney 4 , and Gerhard Laub 2

1 Siemens Healthcare, Portland, USA, United States, 2 Siemens Healthcare, USA, United States, 3 A.A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, MA, United States, 4 Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, United States

The MPRAGE pulse sequence is commonly used for T 1 -weighted imaging. Previous work showed that the relative signal intensity of blood in MPRAGE is dominated by the IR pulse, and by controlling the selectivity of this pulse across multiple measurements one could generate a subtraction MR angiogram (MRA) in addition to a standard T 1 MPRAGE. However, such a subtraction technique is sensitive to motion between the multiple measurements, limiting its applicability. Here we address this shortcoming with the addition of volumetric navigators for prospective motion correction, enabling simultaneous MPRAGE and non-contrast MRA even in the presence of subject motion.

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