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Abstract #3679

19F MRI QUANTIFICATION USING B1 CORRECTION

Ina Vernikouskaya 1 , Alexander Pochert 2 , and Volker Rasche 1

1 Internal Medicine II, University Hospital of Ulm, Ulm, Baden-Wuerttemberg, Germany, 2 Inorganic Chemistry II, University of Ulm, Ulm, Baden-Wuerttemberg, Germany

In contrast to conventional MR contrast agents, 19F signal can be directly measured, instead of indirect measuring the impact on the surrounding environment. However inhomogeneous profile of the excitation field can lead to wrong quantitative results. Therefore B1 mapping has to be performed prior to quantification. Adaptation of one of the existing B1 technique to the problem of 19F signal quantification is proposed in this work. In vitro results are in a good correlation with the simulation prediction. Estimation error for the relative quantification after B1 correction is within 6-7%.

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