A fast and novel groupwise-non-rigid registration methodology for freezing motion in DCE-MRI
KS Shriram 1 , Dattesh D Shanbhag 2 , Sheshadri Thiruvenkadam 2 , Venkata Veerendranadh Chebrolu 2 , Sandeep N Gupta 3 , and Rakesh Mullick 4
Biomedical Signal Analysis Laboratory, GE
Global Research, Bangalore, Karnataka, India,
Image Analysis Laboratory, GE Global Research,
Bangalore, Karnataka, India,
Systems & Signal Processing, GE Global Research,
Niskayuna, NY, United States,
& Biomedical Technologies, GE Global Research,
Bangalore, Karnataka, India
We have introduced a fast group-wise registration scheme
for correction of non-rigid motion in prostate DCE
exams. We demonstrate the robustness of the algorithm in
correcting motion even in presence of coil shine through
artifacts, and retaining signal characteristics.
Overall, motion correction results in lower dispersion
of pK parameters in a given tissue ROI and improved
confidence in interpretation of DCE data.
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