Effective removal of aliasing artifacts in interleaved diffusion weighted EPI using integrated 2D Nyquist correction and multiplexed sensitivity encoded reconstruction
Hing-Chiu Chang 1 and Nan-Kuei Chen 1
Brain Imaging and Analysis Center, Duke
University Medical Center, Durham, North Carolina,
In addition to minuscule motion induced aliasing
artifacts, interleaved EPI based DWI are also
susceptible to Nyquist artifact. 1D Nyquist correction
is routinely used for single-shot and interleaved DWI.
However, in many cases (e.g., oblique-plane EPI), the
Nyquist artifacts due to phase errors along the
phase-encoding direction are significant, which can only
be suppressed with The 2D phase correction Nyquist
correction methods for Nyquist ghost reduction reveal
significant improvement of image quality for both
single-shot and segmented EPI data acquired in oblique
plane or in the presence of cross-term eddy current.
Unfortunately, existing 2D Nyquist correction procedures
are not compatible with interleaved DWI data. To address
this limitation, here we report a novel integrated
approach to simultaneously remove 2D Nyquist artifact
and shot-to-shot phase variations in interleaved DWI
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