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Abstract #3739

Improved contrast-to-noise levels for MS lesion detection on CSF-suppressed heavily T 2 -weighted imaging

Vanessa Wiggermann 1,2 , Enedino Hernndez Torres 2,3 , Anthony Traboulsee 3,4 , David K.B. Li 2,4 , and Alexander Rauscher 2,3

1 Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, 2 Radiology, University of British Columbia, Vancouver, BC, Canada, 3 UBC MRI Research Centre, Vancouver, BC, Canada, 4 Medicine (Neurology), University of British Columbia, Vancouver, BC, Canada

Visualization of cortical lesions on conventional MR images is often challenging due to restricted contrast-to-noise levels. Further, cerebrospinal fluid (CSF) in the vicinity of lesions hampers lesion detection. The here proposed combination of conventional T2-weighted and FLAIR images doubles the contrast-to-noise ratio, while providing suppression of CSF signal. The enhanced contrast may aid automated lesion segmentation and detection of cortical lesions.

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