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Abstract #3882

Implementation of Multiparametric Magnetic Resonance Imaging with High-Resolution Dynamic Contrast-Enhanced and Diffusion-Weighted Magnetic Resonance Imaging at 7T Improves the Assessment of Breast Tumors: A Feasibility Study

Katja Pinker 1 , Pascal Baltzer 1 , Wolfgang Bogner 2 , Doris Leithner 1 , Siegfried Trattnig 2 , Olgica Zaric 2 , Peter Dubsky 3 , Rupert Bartsch 4 , Zsuzsanna Bago-Horvath 3 , Stephan Gruber 2 , Michael Weber 1 , and Thomas H Helbich 1

1 Dept. of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria, 2 Dept. of Biomedical Imaging and Image-guided Therapy, MR Centre of Excellence, Medical University of Vienna, Vienna, Vienna, Austria, 3 Dept. of Surgery, Medical University of Vienna, Vienna, Austria, 4 Dept. of Internal Medicine, Division of Oncology, Medical University of Vienna, Vienna, Austria

The clinical use of multiparametric MR imaging at 7T is feasible with good or excellent image quality. Multiparametric MR imaging of the breast with DCE MR imaging and DWI at 7T seems to have the potential to diagnose breast cancer with high diagnostic accuracy (AUC 0.941). Multiparametric MR imaging of the breast with DCE MR imaging and DWI at 7T improves specificity as compared to interpretation of DCE MRI alone (p=0.031). Multiparametric MR imaging of the breast with DCE MR imaging and DWI at 7T can avoid unnecessary breast biopsies recommended with DCE MR imaging, in our series in 6/8 (75%, p=0.031) of benign breast tumors.

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