Quantification of changes in resting state connectivity in monkey SI cortex following spinal cord injury
Arabinda Mishra 1 , Feng Wang 1 , John C Gore 1 , and Chen Min Li 1
Radiology, Vanderbilt University, Nashville,
TN, United States
Spinal cord is primarily responsible for transmitting
sensory and motor information to and from the brain.
Disruptions following injury on the spinal cord affect
the functional integrity of somatic sensory networks.
This study aims to determine whether the disruption of
afferent inputs from the cervical spinal cord alter the
fine - scale functional connectivity between sub-regions
of SI cortex in the resting state. We performed an ROI
based analysis of resting state BOLD MRI signals
obtained in pre- versus post- lesion conditions in
anesthetized squirrel monkeys at 9.4T to quantify the
inter-regional functional connectivity differences
between the sub-regions of the SI cortex.
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