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Abstract #3914

Combined Echo Volumar Imaging (EVI) and Localized Excitation for Motion Insensitive Fetal fMRI

Rita G. Nunes 1,2 , Giulio Ferrazzi 1 , Anthony Price 1 , Matthew Fox 1 , Christina Malamateniou 1 , Mary Rutherford 1 , and Joseph Hajnal 1,3

1 Centre for the Developing Brain, King's College London, London, United Kingdom, 2 Instituto de Biofisica e Engenharia Biomedica, Universidade de Lisboa, Lisbon, Portugal, 3 Division of Imaging and Sciences and Biomedical Engineerin, King's College London, London, United Kingdom

Initial fMRI studies of the fetal brain have used standard multi-slice 2D EPI sequences and either required intra-volume motion correction or led to a high data rejection rate. We propose combining an EVI readout with localized excitation of the fetal brain to achieve a TR in the order of 150ms therefore significantly reducing sensitivity to motion. This methodology was shown to be feasible in three adult volunteers and a first acquisition test was performed on the fetal brain in utero.

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