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Abstract #3998

Evaluation of Pseudo-Hepatic Anisotropy Artifact in Liver Intravoxel Incoherent Motion (IVIM) based on Clustering Technique

Oi Lei Wong 1,2 , Gladys Goh Lo 3 , Jing Yuan 4 , Wai Kit Chung 3 , Max W. K. Law 4 , Benny W. H. Ho 3 , and Michael D. Noseworthy 2,5

1 Department of Medical Physics and Applied Radiation Science, McMaster University, Hamilton, Ontario, Canada, 2 Imaging Research Center, St.Joseph's Healthcare, Hamilton, Ontario, Canada, 3 Department of Diagnostic & Interventional Radiology, Hong Kong Sanatorium & Hospital, Hong Kong, China, 4 Medical Physics and Research Department, Hong Kong Sanatorium & Hospital, Hong Kong, China, 5 Department of Electrical and Computer Engineering, McMaster Univeristy, Hamilton, Ontario, Canada

Pseudo-hepatic anisotropy artifact has been related to elevation in liver ADC and DT metrics. In this study, we assumed pseudo-hepatic artifact mainly affect perfusion related IVIM metrics. As a result, three type of liver tissue (liver parenchyma, motion contaminated liver parenchyma and vessel) can be identified due to the presence of pseudo-hepatic anisotropy artifact. Based on our result, we have revealed that the effect of pseudo-anitotropy artifact can be minimized using multiple gradient encoding directions.

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