Abstract #4015
High-resolution abdominal diffusion-weighted imaging based on multi-shot and multiplexed sensitivity encoded echo-planar imaging
Hing-Chiu Chang 1 , Arnaud Guidon 2 , Dan Xu 3 , Lloyd Estkowski 4 , Ersin Bayram 5 , Mei-Lan Chu 1,6 , Mustafa R Bashir 1 , Allen W Song 1 , and Nan-kuei Chen 1
1
Duke University Medical Center, Durham,
North Carolina, United States,
2
Global
MR Applications and Workflow, GE Healthcare, Boston, MA,
United States,
3
Global MR Applications and
Workflow, GE Healthcare, Waukesha, WI, United States,
4
Global
MR Applications and Workflow, GE Healthcare, Menlo Park,
CA, United States,
5
Global
MR Applications and Workflow, GE Healthcare, Houston,
TX, United States,
6
National
Taiwan University, Taipei, Taiwan, Taiwan
Recent advancements in multi-shot EPI make it possible
to acquire high-resolution DWI data. Although these
methods have been successfully demonstrated in brain
studies, multi-shot and high-resolution DWI of abdominal
organs (e.g., liver) still cannot be reliably achieved
because of enhanced motion. Here we first demonstrate
that, by integrating navigator-based respiration-gated
multi-shot DWI acquisition and multiplexed sensitivity
encoded reconstruction, abdominal DWI of high-quality
and high-resolution can be successfully achieved. The
developed protocols should prove highly valuable for
clinical examinations that require high-resolution DWI
to detect subtle pathology, such as hydatid cysts,
metastases and other types of lesions of the liver.
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