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Abstract #4030

Preoperative Sentinel Lymph Node Diagnosis with Interstitial MR Lymphography in Cervical Cancer: A Pilot Study

zhengyang zhou 1 , Haiping yu 1 , Ying Hong 2 , and Jing Fang 2

1 Radiology, Affiliated Drum Tower Hospital,School of Medicine,Nanjing University,China, Nanjing, Jiangsu, China, 2 Gynecology, Affiliated Drum Tower Hospital,School of Medicine,Nanjing University,China, Nanjing, Jiangsu, China

Thirty-eight cervical cancer patients underwent preoperatively MR lymphography with gadodiamide and intraoperative lymphatic mapping with isosulfan blue for detection of SLNs. 79 SLNs were preoperatively detected by MR lymphography, whereas 81 SLNs were intraoperatively identified by blue dye-guided surgical dissection, with the detection power of 97.5%. When the combination of characteristics of margin and long-to-short-axis diameter ratio of SLN were taken into consideration, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of MR lymphography for SLN characterization were 94.4%, 96.7%, 89.5%, 98.3%, and 96.2%, respectively. Preoperative MR lymphography offers accurate diagnosis of SLN metastases in cervical cancer.

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