Preoperative Sentinel Lymph Node Diagnosis with Interstitial MR Lymphography in Cervical Cancer: A Pilot Study
zhengyang zhou 1 , Haiping yu 1 , Ying Hong 2 , and Jing Fang 2
Radiology, Affiliated Drum Tower
Hospital,School of Medicine,Nanjing University,China,
Nanjing, Jiangsu, China,
Affiliated Drum Tower Hospital,School of
Medicine,Nanjing University,China, Nanjing, Jiangsu,
Thirty-eight cervical cancer patients underwent
preoperatively MR lymphography with gadodiamide and
intraoperative lymphatic mapping with isosulfan blue for
detection of SLNs. 79 SLNs were preoperatively detected
by MR lymphography, whereas 81 SLNs were
intraoperatively identified by blue dye-guided surgical
dissection, with the detection power of 97.5%. When the
combination of characteristics of margin and
long-to-short-axis diameter ratio of SLN were taken into
consideration, the sensitivity, specificity, positive
predictive value, negative predictive value and accuracy
of MR lymphography for SLN characterization were 94.4%,
96.7%, 89.5%, 98.3%, and 96.2%, respectively.
Preoperative MR lymphography offers accurate diagnosis
of SLN metastases in cervical cancer.
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