A comparison study of Intravoxel Incoherent Motion (IVIM) based DWI and pharmacokinetics analysis based Dynamic Contrast Enhanced MRI in case of cervical cancer
Yan Zhou 1 , Jianyu Liu 2 , Wei He 2 , Yang Shen 2 , Weidan Lu 2 , Huici Zhu 2 , Lizhi Xie 3 , and Zhenyu Zhou 3
Peking University Third Hospital, Beijing,
University Third Hospital, Beijing, China,
Healthcare, Beijing, China
This study aimed at investigating the utility of
intra-voxel incoherent motion model (IVIM) with multi-b
values DWI in diagnosis and grading of cervical cancer.
Moreover, the up to date concept of invasive edge of
tumor was adopted, which had closer relation with tumor
aggressiveness and prognosis. The results showed that
both mono-exponential model and IVIM model could help to
differentiate cervical cancer from normal cervix.
Perfusion fraction (F) at tumor edge showed the best
diagnostic performance in grading cervical squmous
cancer. Therefore, IVIM model might demonstrate
capability on differentiating and grading cervical
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