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Abstract #4040

Introvoxel incoherent motion (IVIM) with multi-b values DWI in the diagnosis and grading of cervical cancer

Yan Zhou 1 , Jianyu Liu 2 , Wei He 2 , Yang Shen 2 , Weidan Lu 2 , Huici Zhu 2 , Dandan Zheng 3 , and Ziheng Zhang 3

1 Peking University Third Hospital, Beijing, Beijing, China, 2 Peking University Third Hospital, Beijing, China, 3 GE Healthcare, Beijing, China

This study aimed at investigating the utility of intra-voxel incoherent motion model (IVIM) with multi-b values DWI in diagnosis and grading of cervical cancer. Moreover, the up to date concept of invasive edge of tumor was adopted, which had closer relation with tumor aggressiveness and prognosis. The results showed that both mono-exponential model and IVIM model could help to differentiate cervical cancer from normal cervix. Perfusion fraction (F) at tumor edge showed the best diagnostic performance in grading cervical squmous cancer. Therefore, IVIM model might demonstrate capability on differentiating and grading cervical cancer.

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