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Abstract #4070

Detection of cytoplasmic lipid within neuroendocrine tumors of the pancreas on chemical shift MRI

YOSHIHIKO FUKUKURA 1 , Koji Takumi 1 , Toshikazu Shindo 1 , Tomokazu Umanodan 1 , Aya Umanodan 1 , Junichi Ideue 1 , Hiroto Hakamada 1 , Kiyohisa Kamimura 1 , Masanori Nakajo 1 , and Takashi Yoshiura 1

1 Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Kagoshima, Japan

We evaluated whether cytoplasmic lipids in pancreatic neuroendocrine tumors (NETs) can be identified on chemical shift MRI and clarify CT and MRI characteristics of lipid-containing pancreatic NETs. Cytoplasmic lipids were histopathologically observed in 15 of 34 NETs. Four of the 15 lipid-containing NETs exhibited high signal on subtraction chemical shift MRI, and signal intensity index of lipid-containing NETs was significantly higher than that of the nonlipid-containing NETs. Lipid-containing NETs had similar appearances to nonlipid-containing NETs on CT and conventional MRI. Pancreatic NETs should be included in the differential diagnosis whenever chemical shift MRI demonstrates lipid components within pancreatic tumors.

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