Abstract #4117
Bone marrow fat behaves differently from abdominal fat, liver fat and serum lipids after a four-week calorie restriction in obese women
Christian Cordes 1 , Michael Dieckmeyer 1 , Beate Ott 2 , Jun Shen 1 , Stefan Ruschke 1 , Marcus Settles 1 , Claudia Eichhorn 2 , Jan S. Bauer 1 , Hendrik Kooijman 3 , Ernst J. Rummeny 1 , Thomas Skurk 2 , Thomas Baum 1 , Hans Hauner 2 , and Dimitrios C. Karampinos 1
1
Diagnostic and Interventional Radiology,
Technische Universitt Mnchen, Mnchen, Germany,
2
Else
Krner Fresenius Center for Nutritional Medicine,
Technische Universitt Mnchen, Mnchen, Germany,
3
Phillips
Healthcare, Hamburg, Germany
Bone marrow is a fat depot that has recently attracted a
considerable research interest due to its unique
connections to metabolism and bone health. The present
study examines the relationship between changes in bone
marrow fat fraction (BMFF), subcutaneous adipose tissue
(SAT), visceral adipose tissue (VAT), liver fat and
serum lipid levels after a four-week calorie restriction
in twenty obese women. BMFF is shown to have smaller
changes after the dietary intervention compared to SAT,
VAT, liver fat and serum lipids. BMFF changes are also
shown to be dependent on the abdominal tissue
distribution before the dietary intervention.
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