Abstract #4127
Reproducibility of Intravoxel Incoherent Motion Diffusion-Weighted Imaging in Small Bowel Crohns Disease
Lianhua Huang 1 , Yihao Guo 2 , Yingjie Mei 3 , Lizhi Zhou 4 , Zeyu Zheng 1 , Yanqiu Feng 5 , Xinying Wang 6 , Jie Feng 1 , Chenggong Yan 1 , and Yikai Xu 1
1
Department of Medical Imaging Center,
Nanfang Hospital, Southern Medical University,
Guangzhou, Guangdong, China,
2
School
of Biomedical Engineering, Southern Medical University,
Guangzhou, Guangdong, China,
3
Philips
healthcare, Guangdong, China,
4
Department
of Biostatistics, School of Public Health and Tropical
Medicine, Southern Medical University, Guangzhou,
Guangdong, China,
5
Guangdong
Provincial Key Laborary of Medical Image Processing,
School of Biomedical Engineering, Southern Medical
University, Guangzhou, Guangdong, China,
6
Department
of Gastroenterology, Nanfang Hospital, Southern Medical
University, Guangzhou, Guangdong, China
The purpose of this study was to test the inter-scan
reproducibility of the IVIM model parameters in
assessing small bowel disease. The patients with
clinically or pathologically confirmed Crohn's disease
underwent DW-MRI on a 3.0T MR scanner.Region growing
method was used to draw the ROI of the whole disease
bowel loop to obtain the IVIM model parameters(f, D*,
D), and the coefficient of determination were calculated
to correct the mean D, f and D* of the ROI. Then the
parameters were compared between two different
acquisitions by using the paired t test. Reproducibility
of parameters were determined by using 95% Bland-Altman
limits of agreement, repeatability coefficients and
intraclass correlation coefficients (ICC). For this
study population, there was good to moderate measurement
reproducibility of D, and D* of small bowel CD.
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