The value of BOLD-MRI in early diagnosis of osteonecrosis of the femoral Head in patients with steroid treatment
Jing Li 1 , Fei Yuan 1 , Quan Zhang 1 , Jun Zhao 1 , and Yu Zhang 2
MRI Department, PingJin Hospital, He Dong
District, TianJin, China,
Healthcare, Beijing, China
Patients who require long-term steroid use are at high
risk for occurrence of osteonecrosis. Early diagnosis of
this complication is essential as the prognosis is
affected by the stage of the disease. However, there is
no consensus on whether screening of bone necrosis
should be performed for long-term glucocorticoid.
Magnetic resonance imaging (MRI) is more sensitive than
plain film for diagnosing early-stage bone necrosis .
Traditionally functional magnetic resonance imaging
(fMRI) using blood oxygenation level-dependent (BOLD)
contrast has appeared to measure vascular oxygenation
change due to neuron activity. This study attempted to
compare BOLD-MRI with conventional MRI sequence on
determining the onset of osteonecrosis of the femoral
head following steroid-related osteonecrosis.
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