Abstract #4224
Assessment of degenerative changes in disc endplates using DCEMRI and T1
Volkan Emre Arpinar 1 and L Tugan Muftuler 1,2
1
Department of Neurosurgery, Medical College
of Wisconsin, Milwaukee, Wisconsin, United States,
2
Center
for Imaging Research, Medical College of Wisconsin,
Wisconsin, United States
Degenerating intervertebral discs sometimes lead to
degenerative changes in adjacent vertebral bodies, which
are classified based on the appearance of vertebral
marrow in T1 and T2 weighted MRI. Although this
classification is widely accepted, those images may not
be sufficiently sensitive to early or transitional
changes. Initial changes associated with vascularization
and edema can be studied by Dynamic contrast enhanced
MRI (DCEMRI). Additional information can be obtained
from T1
,
which is reported to increase in various inflamed
tissues. Our findings show significant increases in both
DCEMRI and T1
with
degeneration in disc endplates.
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