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Abstract #4437

Template-based analysis of multi-parametric MRI data with the Spinal Cord Toolbox

Benjamin De Leener 1 , Augustin Roux 1 , Julien Touati 1 , Simon Levy 1 , Manuel Taso 2,3 , Vladimir Fonov 4 , D. Louis Collins 4 , Virginie Callot 2,3 , and Julien Cohen-Adad 1,5

1 Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, Quebec, Canada, 2 CRMBM UMR 7339, Aix-Marseille Universit, CNRS, Marseille, France, 3 CEMEREM, Hopital de la Timone, Ple dimagerie mdicale, AP-HM, Marseille, France, 4 Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada, 5 Functional Neuroimaging Unit, CRIUGM, Universit de Montral, Montreal, Quebec, Canada

The Spinal Cord Toolbox is an open-source software package for processing and analysis of multi-parametric MRI data of the spinal cord. Main features are automatic spinal cord segmentation (PropSeg), motion correction based on slice-wise regularized registration, web-based interface and template-based registration enabling metric extraction (e.g., cross-sectional area, fractional anisotropy, mean diffusivity, MTR) for any vertebral and spinal level and for specific white matter tracts (e.g., corticospinal, cuneatus). By providing the first semi-automatic framework for registering MR images on a common template, the Spinal Cord Toolbox opens the door to large-group and multi-center studies of spinal cord MRI data.

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