Velocity phase imaging with simultaneous multi-slice EPI reveals respiration driven motion in spinal CSF.
Alexander Beckett 1,2 , Liyong Chen 1,2 , Ajay Verma 3 , and David A Feinberg 1,2
Helens Wills Neuroscience Institute,
University of California, Berkeley, CA, United States,
MRI Technology, Sebastopol, CA, United States,
Idec, MA, United States
Previous research has indicated that respiratory
modulations can influence changes in the velocity of CSF
flow in the brain and spine. We use simultaneous
multi-slice EPI to measure changes in CSF velocity in
multiple levels of the spine simultaneously, and show
modulations in velocity at the same frequency as
respiration. Respiratory modulations are also seen in
non-spine (kidney) ROIs, with a phase opposite to that
of the spinal modulations.
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