Left atrial strain is correlated to atrial fibrosis by late gadolinium enhancement, in an AF population.
Dana C Peters 1 , Daniel Cornfeld 1 , Albert J Sinusas 2 , James S Duncan 1 , Xenios Papademetris 1 , Karl Grunseich 1 , and Sudhakar Chelikani 1
Radiology, Yale School of Medicine, New
Haven, CT, United States,
Yale School of Medicine, New Haven, CT, United States
We tested the hypothesis that left atrial strain was
inversely correlated to atrial fibrosis. Left atrial
strain was assessed using 2-chamber and 4-chamber cine
images in sixteen patients with AF, and 13 control
patients, using atrial contouring and a point-matching
algorithm. Left atrial late gadolinium enhancement (LGE)
was also assessed to obtain a fibrosis score. Average
4-chamber and 2-chamber strains were inversely
correlated to the extent of atrial fibrosis in AF
subjects, but not in controls. Regional strains also
showed strong correlations to LGE.
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