Abstract #4469
Left atrial strain is correlated to atrial fibrosis by late gadolinium enhancement, in an AF population.
Dana C Peters 1 , Daniel Cornfeld 1 , Albert J Sinusas 2 , James S Duncan 1 , Xenios Papademetris 1 , Karl Grunseich 1 , and Sudhakar Chelikani 1
1
Radiology, Yale School of Medicine, New
Haven, CT, United States,
2
Cardiology,
Yale School of Medicine, New Haven, CT, United States
We tested the hypothesis that left atrial strain was
inversely correlated to atrial fibrosis. Left atrial
strain was assessed using 2-chamber and 4-chamber cine
images in sixteen patients with AF, and 13 control
patients, using atrial contouring and a point-matching
algorithm. Left atrial late gadolinium enhancement (LGE)
was also assessed to obtain a fibrosis score. Average
4-chamber and 2-chamber strains were inversely
correlated to the extent of atrial fibrosis in AF
subjects, but not in controls. Regional strains also
showed strong correlations to LGE.
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