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Abstract #4514

High resolution, first pass 3D gadolinium-enhanced venography of the jugular veins: application to multiple sclerosis

Andrew J. Walsh 1 , Derek J. Emery 2 , Ken Warren 3 , Ingrid Catz 3 , and Alan H. Wilman 1

1 Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada, 2 Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada, 3 Neurology, University of Alberta, Edmonton, Alberta, Canada

First pass, 3D gadolinium-enhanced venography of the jugular veins is difficult to perform when seeking both large spatial coverage and high spatial resolution. Particularly when considering routine clinical 1.5 T systems that may not be equipped with dense phased arrays for parallel imaging, capturing the venous phase without overwhelming arterial enhancement becomes difficult. We test first pass Gd-enhanced venography encompassing a large 3D coronal field-of-view at 0.64 mm3 voxel dimensions using a single 36 sec acquisition. High resolution enables proper assessment of venous narrowing. We report on the feasibility in application to 60 subjects, 30 with multiple sclerosis (MS) and 30 healthy controls to examine cerebral venous drainage.

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