An Integer Optimization Technique for Measuring Biventricular Cardiac Strain from Tagged MR Images
Ming Li 1,2 , Himanshu Gupta 3 , Steven G. Lloyd 3 , Louis J. Dell'Italia 3 , and Thomas S. Denney Jr. 1,2
Auburn University MRI Research Center,
Auburn University, Auburn, AL, United States,
and Computer Engineering, Auburn University, AL, United
of Cardiovascular Disease, University of Alabama at
Birmingham, AL, United States
In this abstract we propose an integer optimization
based method for unwrapping harmonic phase from tagged
cardiac MR images and use this method to compute 3D
biventricular cardiac strain through the cardiac cycle.
Compared to the traditional quality guided phase
unwrapping method, the proposed method was considerably
less sensitive to the phase inconsistencies and
therefore required less manual intervention. 5 min of
automated phase unwrapping and 15 min of manual
corrections were required for each study. Biventricular
strains from the proposed method were compared to both a
feature-based and a phase-based method.
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