Evaluation of Upper Airway Collapsibility Using Simultaneous Multi-Slice Real-Time MRI
Ziyue Wu1,2, Weiyi Chen1, Michael C.K. Khoo1, Sally L. Davidson Ward3, and Krishna S. Nayak1
1University of Southern California, Los Angeles, CA, United States, 2Alltech Medical Systems, Solon, OH, United States, 3Children's Hospital Los Angeles, Los Angels, CA, United States
We present a method
for simultaneous multi-slice airway collapsibility measurement based on sparse
golden-angle radial CAIPIRINHA, with acceleration factor up to 33.3. We present
data from patients with obstructive sleep apnea and normal controls. One
interesting finding is that a narrower airway site does not always correspond
to higher collapsibility. This finding may be of interest to sleep surgeons.
Our results also suggest that both compliance and Pclose were significantly
different between healthy controls and OSA patients (P<0.001), and both
measures can potentially serve as biomarkers.
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