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Abstract #0044

Concomitant gradient effects on chemical shift encoded imaging

Timothy J Colgan1,2, Diego Hernando1, Samir D Sharma1, Ann Shimakawa3, and Scott B Reeder1,2,4,5,6

1Radiology, University of Wisconsin, Madison, WI, United States, 2Medical Physics, University of Wisconsin, Madison, WI, United States, 3Global Applied Science Lab, GE Healthcare, Menlo Park, CA, United States, 4Biomedical Engineering, University of Wisconsin, Madison, WI, United States, 5Medicine, University of Wisconsin, Madison, WI, United States, 6Emergency Medicine, University of Wisconsin, Madison, WI, United States

Quantitative chemical shift-encoded (CSE) MRI techniques acquire complex-valued (magnitude and phase) images at multiple echo times (TE), enabling simultaneous mapping of fat-fraction, R2* (=1/T2*) and B0 field. Applications of CSE-MRI include tissue fat quantification, iron quantification and quantitative susceptibility mapping (QSM). Recently, phase shifts due to concomitant gradients (CG) have been identified as a source of error for quantitative CSE techniques, so their effects on fat-fraction, R2* and B0 maps are characterized in this study. CG correction of experimental data demonstrates that the detrimental effects of CG phase shifts can be removed before reconstruction to produce more accurate estimates of the fat-fraction, R2*, and field map measurements.

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