Yunjie Tong1, Kimberly P Lindsey1, Lia M Hocke2, Gordana Vitaliano1, Dionyssios Mintzopoulos1, and Blaise B Frederick1
1McLean Hospital/Harvard Medical School, Belmont, MA, United States, 2Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada
Previously, we have demonstrated that we can
extract systemic low frequency oscillation (sLFO) from resting state (RS) fMRI
data and map its dynamic patterns as it moves through the brain. We have
hypothesized that the dynamic patterns represent the cerebral blood flow. In
this study, we tested this hypothesis by conducting both Dynamic Susceptibility
Contrast scan (bolus tracking) and RS fMRI scan in health subjects. By
comparing the flow patterns of the bolus with that of sLFO, we found that the
flow of sLFO does represent the blood flow, however, mostly in the capillaries
and veins.
