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Abstract #0128

Role of the Intravoxel Incoherent Motion (IVIM) Imaging in the Pre-treatment Prediction and Early Response Monitoring for Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer

Shunan Che1, Chunwu Zhou1, Xinming Zhao1, Jing Li1, and Bing Wu2

1department of radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China, People's Republic of, 2GE Healthcare MR Research China, Beijing, China, People's Republic of

Purpose: to explore whether IVIM can determine pre-treatment differences or monitor early response in breast cancer patients receiving NAC. Materials and Methods: thirty-six patients examined with multiple-b DWI were divided into MHR and NMHR groups. Parameters between MHR and NMHR groups were compared. Results: the D and f value at the baseline and mid-treatment of NAC showed significantly differences between MHR and NMHR. △D and △f were significantly higher in MHR than in NMHR. Conclusion: the D and f value showed potential value in the pre-treatment prediction and early response monitoring to NAC in local advanced breast.

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