Philippa Krahn1,2, Venkat Ramanan2, Labonny Biswas2, Nicolas Yak2, Kevan Anderson2, Jennifer Barry2, Sheldon Singh3, Mihaela Pop1,2, and Graham A Wright1,2
1Medical Biophysics, University of Toronto, Toronto, ON, Canada, 2Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada, 3Cardiology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Here we explored an efficient imaging
protocol for visualizing both the edema (reversible) and necrosis
(irreversible) regions of myocardial injury in RF lesions. Using an MR-guided catheter
system, we performed ablation in swine, immediately followed by T1-based
imaging (IR-SSFP) and T2 mapping (T2-prepared SSFP) for lesion
characterization. The areas of edema segmented from IR-SSFP images and T2 maps were
visually similar and showed good correlation. IR-SSFP is known to visualize
lesion cores at a specific TI--selecting an additional TI which emphasizes
edema, we successfully demonstrated that both regions could be visualized by a
single IR-SSFP acquisition.
