Andreas Merrem1, Jakob Klosowski1, Sabine Hofer1, Klaus-Dietmar Merboldt1, and Jens Frahm1
Single-shot STEAM MRI is a method for black-blood diffusion-weighted
imaging where the use of radiofrequency-refocussed echoes leads to
no image distortions, no susceptibility artifacts, and no violations of the
Carr-Purcell-Meiboom-Gill condition. Despite these favorable properties,
clinical applications have been limited by a low signal-to-noise ratio.
Here, we demonstrate the development of highly undersampled radial
diffusion-weighted single-shot STEAM MRI with iterative reconstruction
to achieve acceptable signal-to-noise for studies of the human brain.