Meeting Banner
Abstract #0242

Quantitative Susceptibility Mapping (QSM) in patients with clinically isolated syndrome (CIS) and multiple sclerosis (MS) - a large cohort study

Ferdinand Schweser1,2, Jesper Hagemeier1, Paul Polak1, Michael G Dwyer1, Niels P Bergsland1,3, Nicola Bertolino1, Bianca Weinstock-Guttman4, Andreas Deistung5, J├╝rgen R Reichenbach5,6, and Robert Zivadinov1,2

1Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, United States, 2MRI Molecular and Translational Research Center, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, United States, 3MR Research Laboratory, IRCCS Don Gnocchi Foundation ONLUS, Milan, Italy, 4Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, United States, 5Medical Physics Group, Department of Diagnostic and Interventional Radiology, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany, 6Michael Stifel Center for Data-driven and Simulation Science Jena, Friedrich Schiller University Jena, Jena, Germany

Quantitative susceptibility mapping (QSM) is the most sensitive technique available for studying tissue iron in vivo. In this work, we applied QSM to more than 1000 patients with multiple sclerosis (MS) and almost 250 patients with clinically isolated syndrome (CIS). Our results provide strong support for changed deep gray matter iron concentrations in MS and CIS.

This abstract and the presentation materials are available to members only; a login is required.

Join Here