Simultaneous evaluation of hemodynamic and functional connectivity in patients with chronic steno-occlusive disease of the cerebrovascular system: A study using BOLD with acetazolamide
1Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, United States, 2Department of Neurology, Emory University, Atlanta, GA, United States
In this paper we applied a temporal-shift
analysis of the BOLD signal to delineate regions with abnormal perfusion in
patients with chronic steno-occlusive disease of the cerebrovascular system. We
proposed an improved method of analysis based on an iterative approach for the temporal
shift analysis. We further explored the effects of acetazolamide, a
vasodilator, on the assessment of hemodynamic compromise using temporal-shift
analysis and functional connectivity.
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