Abstract #0317

4D flow MRI-Derived Hemodynamic Atlases of the Left Ventricle with Hypertrophic Cardiomyopathy Demonstrate Abnormally Elevated Blood Flow Velocities

Pim van Ooij¹, Alex J Barker², Henk A Marquering³, Gustav J Strijkers³, James C Carr², Michael Markl^2,4, and Aart J Nederveen⁵

¹Radiology, Academic Medical Center, Amsterdam, Netherlands, ²Radiology, Northwestern University, Chicago, IL, United States, ³Biomedical Engineering & Physics, Academic Medical Center, Amsterdam, Netherlands, ⁴Biomedical Engineering, Northwestern University, Chicago, IL, United States, ⁵Academic Medical Center, Amsterdam, Netherlands

Altered hemodynamics in the left ventricle (LV) may contribute to heart failure in hypertrophic cardiomyopathy (HCM). The aim of this was study was to employ 4D flow MRI to identify regions with altered velocity in HCM patients based on the concept of 'LV flow heat maps' comparing velocity fields in HCM patients with an atlas derived from healthy controls. In the ejection phase, abnormally elevated velocity was found in the LV outflow tract, whereas the filling phase showed elevated velocity in the LV apex.

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