Abstract #0422

Using 3D ASL to assess the change of cerebral blood flow at high altitude: a longitudinal study

Wenjia Liu¹, Bing Wu², Dandan Zheng², Xin Lou¹, Yulin Wang¹, Li Zheng³, Jie Liu⁴, and Lin Ma¹

¹Department of Radiology, PLA General Hospital, Beijing, China, People's Republic of, ²GE Healthcare, MR Research China, Beijing, Beijing, China, People's Republic of, ³Biomedical Engineering, Peking university, Beijing, China, People's Republic of, ⁴General Hospital of Tibetan Military Area Command, Lhasa, China, People's Republic of

Although cerebral blood flow(CBF) at high altitude have been researched for years, most previous studies are limited by the use of transcranial Doppler. The conclusion of changes in CBF depend on the assumption that the middle cerebral arterial diameter does not alter in hypoxia, but recent studies suggesting that this is not the case. In our study, CBF was measured by 3D arterial spin labeling (ASL) technique at sea level and high altitude in order to seek the cerebrovascular response to altitude environment.

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