Quantitative analysis of diagnosing pancreatic fibrosis using Magnetic resonance elastography
Yu Shi1, qiyong guo1, He An1, Kevin J Glaser2, and Ehman L Richard3
1Department of radiology, Shengjing hospital of China medical university, shenyang, China, People's Republic of, 2Rochester, MN, United States, 3Department of radiology, Mayo Clinic, Rochester, MN, United States
An accurate diagnosis of
pancreatic fibrosis is important in clinical
work. MR elastography (MRE) can be used for staging the degrees
of pancreatic fibrosis that reflects the
severity of chronic pancreatitis.
Our work proved that both fibrosis (P<
0.001) and inflammation (P= 0.014) contribute to higher stiffness of pancreatic
parenchyma, excluding fat deposition (P= 0.082). The sensitivity and specificity was 100% and
86% for diagnosing ≥F2, and 100% and 100% for diagnosing =F3 fibrosis stage, respectively.
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