Joep van Oorschot1, Fatih Guclu2, Peter Luijten1, Tim Leiner1, and Jaco Zwanenburg1
1Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 2Cardiology, University Medical Center Utrecht, Utrecht, Netherlands
Native
T1ρ-mapping is a promising non-contrast enhanced method for fibrosis detection,
that would overcome problems associated with contrast agent use. In this work,
we will evaluate the performance of T1ρ-mapping versus ECV-m and native T1 in
DCM patients. Native T1, native T1ρ and Contrast enhanced T1-maps were acquired
in twelve DCM patients, and 8 healthy volunteers. The T1ρ relaxation time was
significantly higher in the DCM patients (55.6 ± 3.0 ms), compared to the
healthy control subjects (51.5 ± 1.2 ms), p<0.005. A significant correlation
was found between the T1ρ relaxation time and the Extracellular Volume fraction
in patients.
