Laurentius Huber1, Sean Marrett1, Daniel A Handwerker1, Adam Thomas1, Benjamin Gutierrez1, Dimo Ivanov2, Benedikt A Poser2, and Peter A Bandettini1
1Section of Functional Imaging Methods, National Institute of Mental Health, Bethesda, MD, United States, 2MBIC, Maastricht University, Maastricht, Netherlands
We present a fast new method
for obtaining quantitative T1 maps with high spatial (1 mm) and
temporal resolutions (3 s). This method can be useful to investigate
morphological dynamics of brain GM, e.g. during brain activity changes,
plasticity changes, or pathology. The robustness of the developed method is demonstrated
with a finger tapping fMRI experiment. We report a functional GM T1
increase of up to 100 ms, and a GM thickness
increase by up to 0.25 mm.
